Complex Vitreoretinal Surgery - Autologous Translocation of Retinal Pigment Epithelium-choroid Graft
Tipo
In vivo
Zona
Posterior segment
Enfermedad objetivo

Age-related Macular Degeneration (AMD)

Especies

Pig (Sus scrofa domestica)

Descripción

Age-related macular degeneration (AMD) is a chronic, bilateral and very disabling disease and thus a leading cause of vision loss worldwide. Replacement of the diseased retinal pigment epithelium (RPE) cells is considered an attractive possibility for cases of AMD not suitable to be managed with the standard treatments. In this model autologous translocation of the choroid and RPE is carried out in porcine eyes closely following the technique described by van Meurs & Van Den Biesen (2003).

Referencias académicas
  • Fernandez-Bueno I, et al. Histology and immunochemistry evaluation of autologous translocation of RPE-choroid graft in porcine eyes. Acta Ophthalmol Scan 2013;91:e125-32
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