Endophthalmitis (Intravitreal S. Aureus)

Bacterial endophthalmitis is an infection and inflammation of the posterior segment of the eye which can result in significant loss of visual acuity. Experimental animal models have been used to examine various aspects of the pathogenesis and pathophysiology of bacterial endophthalmitis, to further the development of anti-inflammatory treatment strategies, and to evaluate the pharmacokinetics and efficacies of antibiotics. In this model, rabbits were inoculated intravitreally with 200 CFU of a typed strain of S. aureus.